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US · guidance

CMS SOM App. Y, Tag Z197

(Standard) §486.346(c) The OPO must develop and follow a written protocol for

activein force · 2026-07-22 – presentas-observed

packaging, labeling, handling, and shipping organs in a manner that ensures their

arrival without compromise to the quality of the organ. The protocol must include

procedures to check the accuracy and integrity of labels, packaging, and contents

prior to transport, including verification by two individuals, one of whom must be

an OPO employee, that information listed on the labels is correct.

Interpretive Guidelines §486.346(c)

The OPO should develop its written protocols for packaging, labeling, handling and

shipping organs and the protocols should be consistent with OPTN rule 5.0 Standardized

Packaging and Transporting of Organ and Tissue Typing Materials.

The protocols must also require that an OPO staff member verify in writing that the ABO

indicated on the container label and the donor information documents being sent with the

organ are accurate. A second person, other than the person originally performing

verification of the labeling and documentation requirements, must also verify their

accuracy in writing. Review the sample of donor records to verify that the OPO has

documentation to confirm that this double confirmation occurred and was documented.

History

Rev. 115, Issued: 05-23-14, Effective: 05-23-14, Implementation: 05-23-14

Provenance

Source
cms.gov
Retrieved
2026-07-22
Edition
som-2026-07-22
Content hash
504b5622da358ed03166f724e80bfdffe7005eb70eeeb75aeae348a4b3efd57a
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