US · guidance
CMS SOM App. C, Tag D5473
§493.1256 Standard: Control procedures
(e)(2) Each day of use (unless otherwise specified in this subpart), test staining
materials for intended reactivity to ensure predictable staining characteristics.
Control materials for both positive and negative reactivity must be included, as
appropriate.
Interpretive Guidelines §493.1256(e)(2)
The laboratory must check routine stain Hematoxylin and Eosin each day for intended
response, and predicted characteristics of the stain.
Interpretive Guidelines §493.1256(e)(2)-(e)(3)
Acid-fast stains must be checked each day of use for positive and negative reactivity.
History
Rev. 233; Issued: 09-12-25; Effective: 09-12-25; Implementation: 09-12-25
Provenance
- Source
- cms.gov
- Retrieved
- 2026-07-22
- Edition
- som-2026-07-22
- Content hash
5acfb738c9fdfb3ec89e87a28d826cd08468bd7e4da6069c3963c5eb4247f44e
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