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US · guidance

CMS SOM App. C, Tag D3000

§493.1100 Condition: Facility administration

activein force · 2026-07-22 – presentas-observed

Each laboratory that performs nonwaived testing must meet the applicable

requirements under §§493.1101 through 493.1105, unless HHS approves a

procedure that provides equivalent quality testing as specified in Appendix C of the

State Operations Manual (CMS Pub. 7).

Interpretive Guidelines §493.1100

To determine which tests are categorized as waived or nonwaived (i.e. moderate or high

complexity tests), refer to the following web link for the FDA categorization database

(http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCLIA/Search.cfm?sAN=0). Test

systems, assays, and examinations not yet classified are considered high complexity.

Significant deficiencies cited under this condition may also indicate deficiencies under

personnel responsibilities.

History

Rev. 233; Issued: 09-12-25; Effective: 09-12-25; Implementation: 09-12-25

Provenance

Source
cms.gov
Retrieved
2026-07-22
Edition
som-2026-07-22
Content hash
31533ac969efdcb11b322c020e00a6879d1888958ddc11a6b1800a0d2caa4a54
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