US · guidance
CMS Pub. 100-08, ch. 4, § 4.1
Introduction
The CMS Pub. 100-08, Program Integrity Manual (PIM), reflects the principles, values,
and priorities of the Medicare Integrity Program (MIP). The primary principle of
program integrity (PI) is to pay claims correctly. To meet this goal, Unified Program
Integrity Contractors (UPICs), Investigations Medicare Drug Integrity Contractor (I-MEDIC), Supplemental Medical Review Contractors (SMRC) and Medicare
Administrative Contractors (MACs) must ensure that Medicare pays the right amount
for covered and correctly coded services rendered to eligible beneficiaries by legitimate
providers. The focus of the UPICs, SMRCs and MACs shall be to ensure compliance
with Medicare regulations, refer suspected fraud and abuse to our Law Enforcement
(LE) partners, and/or recommend revocation of providers that are non-compliant with
Medicare regulation and policies. The Centers for Medicare & Medicaid Services (CMS)
follows four parallel strategies in meeting this goal:
1. Prevent fraud through effective enrollment and education of
providers/suppliers and beneficiaries;
2. Encourage early detection (through, for example, the Fraud Prevention
System (FPS), medical review (MR) and data analysis);
3. Coordinate closely with partners, including other UPICs, SMRCs, MACs, LE
agencies, and State PI units; and
4. Enact fair and firm enforcement policies.
The UPICs shall coordinate with their Contracting Officer’s Representative(s) (COR)
and their Business Function Lead(s) (BFL) to fulfill all direction as described in the
PIM. For all guidance and instruction described in this chapter, the UPIC shall directly
contact the appropriate UPIC BFL, with a copy to the UPIC COR, for any Technical
issues and/or questions (i.e. process related issues/inquiries, workload prioritization,
etc.). Additionally, the UPIC shall directly contact the UPIC COR, with a copy to the
appropriate UPIC BFL, for any Business issues and/or questions (i.e., level of effort
concerns, funding issues, etc.).
The UPICs shall follow the PIM to the extent outlined in their respective task orders’
Statement of Work (SOW). The UPICs shall only perform the functions outlined in the
PIM as they pertain to their own operation. The UPICs, in partnership with CMS, shall
be proactive and innovative in finding ways to enhance the performance of PIM
guidelines.
For this entire chapter, any reference to UPICs shall also apply to the I-MEDIC, unless
otherwise noted or identified in the Contractors’ SOW. MACs shall follow the PIM in
accordance with their SOW.
To facilitate understanding, the terms used in the PIM are defined in PIM Exhibit 1. The
acronyms used in the PIM are listed in PIM Exhibit 23.
History
(Rev. 11962; Issued: 04-21-23; Effective: 05-22-23; Implementation: 05-22-23)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
4ba3232f24e1deb4776bbd401484db491109b07119889bf3656842996f51fe14
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