US · guidance
CMS Pub. 100-04, ch. 32, § 260.1.1
Hospital Billing Instructions
A - Hospital Outpatient Claims
For hospital outpatient claims, hospitals must bill covered dermal injections for
treatment of facial LDS by having all of the required elements on the claim:
1. A line with HCPCS codes Q2026 or Q2027 with a Line Item Date of service
(LIDOS) on or after March 23, 2010,
NOTE: Q2027 is replaced with Q2028 effective 1/1/14 as per the 2014 HCPCS
update.
2. A line with HCPCS code G0429 with a LIDOS on or after March 23, 2010,
3. If ICD-10-CM is applicable, ICD-10-CM diagnosis codes B20 Human
Immunodeficiency Virus (HIV) disease and E88.1 Lipodystrophy, not elsewhere
classified
The applicable NCD is 250.5 Facial Lipodystrophy.
B - Outpatient Prospective Payment System (OPPS) Hospitals or Ambulatory
Surgical Centers (ASCs):
For line item dates of service on or after March 23, 2010, and until HCPCS codes Q2026
and Q2027 are billable, facial LDS claims shall contain a temporary HCPCS code C9800,
instead of HCPCS G0429 and HCPCS Q2026/Q2027, as shown above.
NOTE: Q2027 is replaced with Q2028 effective 1/1/14 as per the 2014, HCPCS
update.
C - Hospital Inpatient Claims
Hospitals must bill covered dermal injections for treatment of facial LDS by having all of
the required elements on the claim:
C. Discharge date on or after March 23, 2010,
D. If ICD-10-PCS is applicable,
• ICD-10-PCS procedure code 3E00XGC Introduction of Other Therapeutic
Substance into Skin and Mucous Membrances, External Approach, or
E. If ICD-10-CM is applicable on or after 10/01/2015,
• ICD-10-CM diagnosis codes B20 Human Immunodeficiency Virus [HIV]
disease and E88.1 Lipodystrophy not elsewhere classified.
A diagnosis code for a comorbidity of depression may also be required for coverage on an
outpatient and/or inpatient basis as determined by the individual Medicare contractor’s
policy.
History
(Rev. 11021; Issued: 10-01-21; Effective: 10-29-21; Implementation: 10-29-21)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
f867d395e7c24dfd18ac6a9c0efbe85c833170990e72540ccebda655a0593638
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