US · guidance
CMS Pub. 100-04, ch. 23, § 20.9.3.2
Medically Unlikely Edits (MUEs)
All HCPCS/CPT codes with MUE values have an MAI.
MUEs for HCPCS/CPT codes with an MAI of “1”: MUEs for HCPCS/CPT codes with an MAI of “1” will
be adjudicated as a claim line edit.
MUEs for HCPCS/CPT codes with an MAI of “2”: MUEs for HCPCS/CPT codes with an MAI of “2” are
absolute date of service edits. These are “per day edits based on policy”. HCPCS/CPT codes with an MAI
of “2” have been rigorously reviewed and vetted within CMS and obtain this MAI designation because UOS
on the same date of service in excess of the MUE value would be considered contrary to statute, regulation,
or subregulatory guidance. Subregulatory guidance includes clear correct coding policy that is binding on
both providers or suppliers and the MACs. As stated in CR 8853, while Qualified Independent Contractors
(QICs) are not bound by subregulatory guidance, they should understand the policy nature of the MAI “2”
indicator when considering whether to pay UOS in excess of the MUE value if claim denials based on these
edits are appealed.
Limitations created by anatomical or coding restrictions are incorporated in correct coding policy, both in
the Health Insurance Portability & Accountability Act of 1996 (HIPAA) mandated coding descriptors and
CMS approved coding guidance as well as specific guidance in the CMS and NCCI Policy manuals. For
example, it would be contrary to correct coding policy to report more than 1 unit of service for "ventilation
assist and management . . . initial day" because such usage could not accurately describe 2 initial days of
management occurring on the same date of service as would be required by the code descriptor.
CMS establishes edits with an MAI of “2” based directly on regulation, statute or subregulatory guidance.
MUEs for HCPCS/CPT codes with an MAI of “3”: MUEs for HCPCS/CPT codes with an MAI of “3” are
date of service edits. These are “per day edits based on clinical benchmarks”. If claim denials based on these
edits are appealed, MACs may pay UOS in excess of the MUE value if there is adequate documentation of
medical necessity of correctly reported units. If MACs have pre-payment evidence (e.g. medical review) that
UOS in excess of the MUE value were actually provided, were correctly coded, and were medically
necessary, the MACs may bypass the MUE for a HCPCS/CPT code with an MAI of “3” during claim
processing, reopening, or redetermination, or in response to effectuation instructions from a reconsideration
or higher level appeal.
General Instructions on MUEs:
• MUEs are set high enough to allow for medically likely daily frequencies of services provided in most
settings. Because MUEs are based on current coding instructions and practices, MUEs are prospective
edits applicable to the time period for which the edit is effective. A change in an MUE is not retroactive
and has no bearing on prior services unless specifically updated with a retroactive effective date. In the
unusual case of a retroactive MUE change, MACs are not expected to identify claims but should reopen
impacted claims that providers or suppliers bring to their attention.
• Since MUEs are auto-deny edits, denials may be appealed. Appeals shall be submitted to the appropriate
MAC not the NCCI contractor. MACs adjudicating an appeal for a claim denial for a HCPCS/CPT code
with an MAI of “1” or “3” may pay correctly coded correctly counted medically necessary UOS in
excess of the MUE value.
• A denial of services due to an MUE is a coding denial, not a medical necessity denial. The presence of
an ABN shall not shift liability to the beneficiary for UOS denied based on an MUE. If during reopening
or redetermination medical records are provided with respect to an MUE denial for an edit with an MAI
of “3”, MACs will review the records to determine if the provider or supplier actually furnished units in
excess of the MUE, if the codes were used correctly, and whether the services were medically reasonable
and necessary. If the units were actually provided, but one of the other conditions is not met, a change in
denial reason may be warranted (for example, a change from the MUE denial based on incorrect coding
to a determination that the item/service is not reasonable and necessary under section 1862(a)(1)). This
may also be true for certain edits with an MAI of “1.” CMS interprets the notice delivery requirements
under Section 1879 of the Social Security Act (the Act) as applying to situations in which a provider or
supplier expects the initial claim determination to be a reasonable and necessary denial. Consistent with
NCCI program guidance, denials resulting from MUEs are not based on any of the statutory provisions
that give liability protection to beneficiaries under section 1879 of the Social Security Act. Thus, ABN
issuance based on an MUE is NOT appropriate. A provider or supplier may not issue an ABN in
connection with services denied due to an MUE and cannot bill the beneficiary for UOS denied based on
an MUE.
• If a procedure is performed bilaterally and the HCPCS/CPT code descriptor does not state that it is a
unilateral or bilateral procedure, report bilateral surgical procedures on a single claim line with modifier
50 and one (1) unit of service. For specific instructions for Ambulatory Surgical Centers, see the
Medicare Claims Processing Manual, Chapter 14, Section 40.5.
When modifier 50 is required by manual or coding instructions, claims submitted with 2 lines or 2 units
and anatomic modifiers will be denied for incorrect coding. MACs may reopen or allow resubmission of
those claims in accordance with their policies and with the policy in the Medicare Claims Processing
Manual, Chapter 34, Section 10.1.
Clerical errors (which include minor errors and omissions) may be treated as reopenings.
• Providers or suppliers may change and resubmit their own claims where possible but during reopening
MACs may, when necessary, correct the claim to modifier 50 from an equivalent 2 units of bilateral
anatomic modifiers. The original submitted version of the claim is retained in the Medicare IDR
(Integrated Data Repository).
• Providers or suppliers shall use anatomic modifiers (e.g., RT, LT, FA, F1-F9, TA, T1-T9, E1-E4) and
report procedures with differing modifiers on individual claim lines when appropriate. Many MUEs are
based on the assumption that correct modifiers are used.
• A/B MACs shall include with the review determination the more detailed explanation of the correct
coding initiative edit, which can be found in the standard correspondence language for A/B MACs in the
Medicare NCCI Correspondence Language Manual.
• MACs shall assign MSN 15.6. CARC 151 with Group Code CO for claims that fail the MUE edits,
when the UOS on the claim exceeds the MUE value, and deny the entire claim line(s) for the relevant
HCPCS/CPT code.
20.9.4 Reserved for future use
(Rev. 4465; Issued: 11-15-19, Effective: 01-30-19, Implementation: 01-30-19)
20.9.4.1 Reserved for future use
(Rev. 4465; Issued: 11-15-19, Effective: 01-30-19, Implementation: 01-30-19)
History
(Rev. 14428, Issued:06-16-26; Effective:07-16-26; Implementation:07-16-26)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
a5a950f1a3ac99f972c9d632339a6f4ff1b88e8758ad0668a2f745400bc80d6a
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