US · guidance
CMS Pub. 100-04, ch. 17, § 100.2.3.1
Further Editing on the Prescription Order Number
Prescription order numbers submitted with inappropriate spaces inserted disrupt the
matching process between the physician/provider claims and the vendor claims.
Effective for claims processed on or after July 7, 2008, contractors shall implement edits
to treat these claims as unprocessable.
Prescription order numbers submitted with less than 10 characters on CAP claims will
also be treated as unprocessable. For either of the two prior situations, the contractor
shall use the following remittance advice messages and associated codes when
rejecting/denying claims under this policy. This CARC/RARC combination is compliant
with CAQH CORE Business Scenario Two.
Group Code: CO
CARC: 16
RARC: N388
MSN: N/A
In addition, CAP physicians/providers and CAP vendors may not submit new claims
(processed as entry code 1) with prescription order numbers that they have already
submitted on previously adjudicated claims, even if the prior claims have been denied.
The CAP physicians/providers and CAP vendors must request an adjustment to the
original claim (processed as entry code 5). Claims that have been returned as
unprocessable may be accepted with the original prescription order number when
resubmitted after being corrected.
CWF will create a new utilization error code that will be returned when it receives a
claim that has a prescription order number on it that matches a prescription order number
already on file from a different claim. This claim could be from the same
physician/provider/supplier or a different physician/provider/supplier. CWF coding will
differentiate between claims from the physicians/providers and claims from the CAP
vendors. It will be acceptable to allow a claim with a duplicate prescription order number
as long as one claim is from a physician/provider and the other claim is from the vendor.
This will allow the prescription order number matching process to continue.
Contractors shall treat as unprocessable the entire claim when a claim receives the new
CWF utilization error code. Contractors shall not allow appeals rights on claims treated
as unprocessable in response to the new error code.
The contractor shall use the following remittance advice messages and associated codes
when rejecting/denying claims under this policy. This CARC/RARC combination is
compliant with CAQH CORE Business Scenario Two.
Group Code: CO
CARC: 18
RARC: N389, M16 and N185
MSN: N/A
History
(Rev. 3721, Issued: 02-24-17, Effective: 05-25-17, Implementation: 05-25-17)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
99dc0fbc699e989c2d7e80be2848a1101bfd96a874cc0b9e3672131b81d10a1d
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