US · guidance
CMS Pub. 100-04, ch. 16, § 90.2
Organ or Disease Oriented Panels
Prior to January 1, 2018, organ or disease panels must be paid at the lower of the billed
charge, the fee amount for the panel, or the sum of the fee amounts for all components.
Payment for the total panel may not exceed the sum total of the fee amounts for
individual covered tests. All Medicare coverage rules apply.
The Medicare shared systems must calculate the correct payment amount. The CMS
furnishes fee prices for each code but the A/B MAC (A) or (B) system must compare
individual codes billed with codes and prices for related individual tests. (With each
HCPCS update, HCPCS codes are reviewed and the system is updated). Once the codes
are identified, A/B MACs (A) and (B) publish panel codes to providers.
The only acceptable Medicare definition for the component tests included in the CPT
codes for organ or disease oriented panels is the American Medical Association (AMA)
definition of component tests. The CMS will not pay for the panel code unless all of the
tests in the definition are performed. If the laboratory has a custom panel that includes
other tests, in addition to those in the defined CPT or HCPCS panels, the additional tests,
are billed separately in addition to the CPT or HCPCS panel code.
NOTE: If a laboratory chooses, it can bill each of the component tests of these panels
individually, but payment will be based upon the above rules.
Effective for claims with dates of service on or after January 1, 2019, laboratories shall
bill the HCPCS panel test code and not unbundle the individual components if all
components of the HCPCS panel are performed. Claims will be returned as
unprocessable/rejected if the HCPCS panel test code is not billed. Providers and suppliers
are required to submit all AMCC laboratory test HCPCS for the same beneficiary,
performed on the same date of service on the same claim. This billing policy applies
when:
a). Submitting a complete organ disease panel; or
b). Submitting individual component tests of an organ disease panel when all components
of the panel were not performed.
TABLE OF CHEMISTRY PANELS
Hepatic
Function
Panel
80076
Basic
Metabolic
Panel
(Calcium,
ionized)
80047
Basic
Metabolic
Panel
(Calcium,
total)
80048
Comprehensive
Metabolic
Panel
80053
Renal
Function
Panel
80069
Lipid0F
1
Panel
80061
Electrolyte
Panel
80051
Chemistry CPT
Albumin 82040 X X X
Alkaline
phosphatase
84075 X X
ALT (SGPT) 84460 X X
AST (SGOT) 84450 X X
Bilirubin, total 82247 X X
Bilirubin, direct 82248 X
Calcium 82310 X X X
Calcium ionized 82330 X
Chloride 82435 X X X X X
Cholesterol 82465 X
CK, CPK 82550
CO2
(bicarbonate)
82374 X X X X X
Creatinine 82565 X X X X
GGT 82977
Glucose 82947 X X X X
LDH 83615
Phosphorus 84100 X
Potassium 84132 X X X X X
Protein 84155 X X
Sodium 84295 X X X X X
Triglycerides 84478 X
Urea nitrogen
(BUN)
84520 X X X X
Uric Acid 84550
History
(Rev. 4299, Issued: 05-03-19, Effective: 01-01-19, Implementation: 10-07-19)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
1e285cc55931b9b5523925836713a37ba0d9eed3af5a067ddcec05d2e2ce8985
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