US · guidance
CMS Pub. 100-04, ch. 8, § 60.4.4.1
Payment for Epoetin Alfa (EPO) in Other Settings
With the implementation of the ESRD PPS, ESRD-related EPO is included in ESRD PPS
payment amount and is not separately payable on Part B claims with dates of service on
or after January 1, 2011 for other providers with the exception of a hospital billing for an
emergency or unscheduled dialysis session.
In the hospital inpatient setting, payment under Part A is included in the DRG.
In the hospital inpatient setting, payment under Part B is made on bill type 12x. Hospitals
report the drug units based on the units defined in the HCPCS description. Hospitals do
not report value code 68 for units of EPO. For dates of service prior to April 1, 2006,
report EPO under revenue code 0636. For dates of service from April 1, 2006 report
EPO under the respective revenue code 0634 for EPO less than 10,000 units and revenue
code 0635 for EPO over 10,000 units. Payment will be based on the ASP Pricing File.
In a skilled nursing facility (SNF), payment for EPO covered under the Part B EPO
benefit is not included in the prospective payment rate for the resident’s Medicare-covered SNF stay.
In a hospice, payment is included in the hospice per diem rate when treatment is related
to the terminal illness.
For a service furnished by a physician or incident to a physician’s service, payment is
made to the physician by the A/B MAC (B) in accordance with the rules for ‘incident to”
services. When EPO is administered in the renal facility, the service is not an “incident
to” service and not under the “incident to” provision.
History
(Rev. 10640, Issued:08-06-21, Effective:09-07-21, Implementation:09-07-21)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
cb038cf48fa3587dae0b8f7ef5370b0dd19f1ce7c4590afb03644474d26177ba
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