US · guidance
CMS Pub. 100-04, ch. 4, § 231.9
Billing for Pheresis and Apheresis Services
Apheresis/pheresis services are billed on a per visit basis and not on a per unit basis.
OPPS providers should report the charge for an Evaluation and Management (E&M) visit
only if there is a separately identifiable E&M service performed which extends beyond
the evaluation and management portion of a typical apheresis/pheresis service. If the
OPPS provider is billing an E&M visit code in addition to the apheresis/pheresis service,
it may be appropriate to use the HCPCS modifier -25.
History
(Rev. 496, Issued: 03-04-05, Effective: 07-01-05, Implementation: 07-05-05)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
ee39f88c1734838edab27a900e9420071de2534397a19795d2d2fcd597aa368f
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