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US · guidance

CMS Pub. 100-04, ch. 4, § 231.5

Billing for Irradiation of Blood Products

activein force · 2026-08-25 – presentas-observed

In situations where a beneficiary receives a medically reasonable and necessary

transfusion of an irradiated blood product, an OPPS provider may bill the specific

HCPCS code which describes the irradiated product, if a specific code exists, in addition

to the CPT code for the transfusion. If a specific HCPCS code for the irradiated blood

product does not exist, then the OPPS provider should bill the appropriate HCPCS code

for the blood product, along with CPT code 86945 (irradiation of blood product, each

unit).

EXAMPLE: If an OPPS provider transfuses the product described by P9040 (red blood

cells, leukocytes reduced, irradiated, each unit), it would not be appropriate to bill an

additional CPT code for irradiation of the blood product since charges for irradiation

should be included in the charge for P9040.

History

(Rev. 496, Issued: 03-04-05, Effective: 07-01-05, Implementation: 07-05-05)

Provenance

Source
cms.gov
Retrieved
2026-08-25
Edition
iom-2026-08-25
Content hash
37bb715736f23b79a240ad9940c2f13a7f6072877ac82f738cccbf48412bea5d
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