US · guidance
CMS Pub. 100-03, ch. 1, § 230.12
Dimethyl Sulfoxide (DMSO)
CIM 45-23
The DMSO is an industrial solvent produced as a chemical byproduct of paper production from wood pulp.
The Food and Drug Administration has determined that the only purpose for which DMSO is safe and
effective for humans is in the treatment of the bladder condition, interstitial cystitis. Therefore, the use of
DMSO for all other indications is not considered to be reasonable and necessary. Payment may be made for
its use only when reasonable and necessary for a patient in the treatment of interstitial cystitis.
History
(Rev. 1, 10-03-03)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
2d124e5c0603f53c9f6b85927cc9947966bcc5250bb8e25b2a3ec98686a61856
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