US · guidance
CMS Pub. 100-03, ch. 1, § 200.1
Nesiritide for Treatment of Heart Failure Patients (Effective March 2, 2006)
A. General
Nesiritide (Natrecor®) is Food and Drug Administration (FDA)-approved for the intravenous treatment of
patients with acutely decompensated congestive heart failure (CHF) who have dyspnea (shortness of breath)
at rest or with minimal activity. Nesiritide is not self-administered.
B. Nationally Covered Indications
N/A
C. Nationally Non-Covered Indications
Effective for dates of service on or after March 2, 2006, the Centers for Medicare & Medicaid Services has
determined that there is sufficient evidence to conclude that the use of Nesiritide for the treatment of CHF is
not reasonable and necessary for Medicare beneficiaries in any setting.
D. Other
Effective for dates of service on or after March 2, 2006, this determination applies only to the treatment of
CHF and does not change Medicare Administrative Contractor (MAC) discretion to cover other off-label
uses of Nesiritide or use consistent with the current FDA indication for intravenous treatment of patients
with acutely decompensated CHF who have dyspnea at rest or with minimal activity.
History
(Rev. 173, Issued: 09-04-14, Effective: Upon Implementation: of ICD-10, Implementation: Upon Implementation of ICD-10)
Provenance
- Source
- cms.gov
- Retrieved
- 2026-08-25
- Edition
- iom-2026-08-25
- Content hash
ec1a6e9845b2fe678a11c751250a8765b14638229d821003bac6745c499307e6
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