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CMS Pub. 100-02, ch. 15, § 50.5.2.2

Medicare Coverage of Epoetin Alfa (Procrit) for Preoperative Use

activein force · 2026-08-25 – presentas-observed

PM-AB-99-59, Dated 8/1/99

This instruction pertains exclusively to the preoperative surgical indication of the drug Procrit, in which it is

administered to specific patients prior to surgery to reduce risk of transfusion. It does not affect Medicare

policies related to other Food and Drug Administration (FDA) approved uses of Procrit. It is not a national

coverage decision.

Procrit as Preventive Service

The A/B MAC (B) may determine that Procrit is covered for individuals who:

1. Are undergoing hip or knee surgery

2. Have an anemia with a hemoglobin between 10 and 13 mg/dL;

3. Are not a candidate for autologous blood transfusion;

4. Are expected to lose more than 2 units of blood; and

5. Have had a workup so that their anemia appears to be that of chronic disease.

The preoperative use of Procrit may be afforded to these individuals when A/B MACs (B), exercising their

discretion, determine that this treatment is reasonable and necessary. In other cases, Procrit is considered a

preventive service and therefore not covered.

History

(Rev. 1, 10-01-03)

Provenance

Source
cms.gov
Retrieved
2026-08-25
Edition
iom-2026-08-25
Content hash
f432bcc46105e9494fb51713ed10b8468b0d649a66efc5b52e97154acdea09f4
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